Dampening Immunogenicity of a Non-Human Protease to Induce Rapid, Deep & Sustained Catalytic Degradation of IgG in Autoimmune Disease
Time: 2:30 pm
day: Conference Day Two
Details:
- Training of accurate AI tools for immunogenicity engineering using Big Data mutational scans of HLA class II epitopes
- Development of a bacterial IgG protease that rapidly and durably depletes antibodies in an animal models with quiet immunogenicity
- Treatment of autoimmune disease in animal models that mimic autoantibody-driven disease in humans
